Across TCGA patient cohorts, SLC8A1 mutation is significantly associated with the total protein of many other genes, with 92 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC8A1-associated genes across cancer lineages are Cyclin-B1, TFRC, and ASNS. Each is linked with SLC8A1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLC8A1-to-partner and partner-to-SLC8A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC8A1→partner) and Y-score (partner→SLC8A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.709	+1.874	<.001	<.001	3	5
LUAD	TFRC →	+0.694	+3.700	<.001	.001	3	4
COAD	ASNS →	+0.689	+2.467	<.001	.011	3	4
UCEC	Caspase-7-cleavedD198 →	+0.704	+1.678	<.001	<.001	3	4
LUAD	mTOR_pS2448 →	-0.243	-2.169	<.001	.003	3	3
LUAD	MYH11 →	-0.767	-3.584	.015	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 92 associations by consensus.

Exploration

SLC8A1 survival (RNA) · tumor vs normal (RNA) · all SLC8A1 data types