Across TCGA cell cohorts, SLC8A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,223 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SLC8A1-associated GO terms across cancer lineages are Relaxation of smooth muscle, Regulation of RNA polymerase II transcription preinitiation complex assembly, and Response to caffeine. Each is linked with SLC8A1 in more than 17 cancer types. Because this analysis shows association rather than direction, both SLC8A1-to-partner and partner-to-SLC8A1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC8A1→partner) and Y-score (partner→SLC8A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Relaxation of smooth muscle →	-0.302	-2.530	<.001	<.001	3	18
SOFT_TISSUE	Regulation of RNA polymerase II transcription preinitiation complex assembly →	+0.124	+1.905	<.001	<.001	3	11
PANCREAS	Response to caffeine →	-0.185	-0.862	.005	.003	3	10
CNS	Regulation of stress-activated protein kinase signaling cascade →	+0.072	+1.097	<.001	<.001	3	10
BREAST	Regulation of intracellular transport →	+0.051	+1.376	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Negative regulation of cytosolic calcium ion concentration →	-0.272	-1.115	<.001	.009	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,223 associations by consensus.

Exploration

SLC8A1 survival (RNA) · tumor vs normal (RNA) · all SLC8A1 data types