SLC7A8

Across TCGA patient cohorts, SLC7A8 protein abundance is significantly associated with the RNA expression of many other genes, with 11,524 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLC7A8-associated genes across cancer lineages are NELL2, NRSN1, and FRMD6-AS2. Each is linked with SLC7A8 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC7A8-to-partner and partner-to-SLC7A8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC7A8 versus NELL2 in UCEC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A8→partner) and Y-score (partner→SLC7A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NELL2 →	+2.698	+1.413	.008	.005	3	4
UCEC	NRSN1 →	+1.959	+1.305	.001	.008	3	3
LSCC	FRMD6-AS2 →	+1.231	+0.794	<.001	<.001	3	3
BRCA	SYNGR1 →	+1.006	+0.679	<.001	.001	3	3
BRCA	SLC9A3R1 →	+1.444	+0.768	<.001	<.001	3	3
UCEC	CD22 →	+1.012	+1.664	.003	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,524 associations by consensus.

SLC7A8 vs NELL2 — UCEC

Explore this scatter interactively →