SLC7A8

Across TCGA cell cohorts, SLC7A8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,953 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SLC7A8-associated GO terms across cancer lineages are Aerobic respiration, Proton transmembrane transport, and Negative regulation of mRNA processing. Each is linked with SLC7A8 in more than 8 cancer types. Because this analysis shows association rather than direction, both SLC7A8-to-partner and partner-to-SLC7A8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic respiration grouped by SLC7A8-low versus SLC7A8-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A8→partner) and Y-score (partner→SLC7A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Aerobic respiration →	+0.104	+1.730	<.001	<.001	3	9
LIVER	Proton transmembrane transport →	+0.076	+1.430	.001	.001	3	9
BLOOD_Leukemia	Negative regulation of mRNA processing →	+0.053	+1.214	.009	<.001	3	9
OESOPHAGUS	Negative regulation of DNA-templated transcription, elongation →	+0.119	+4.088	.003	.001	3	8
PANCREAS	Regulation of syncytium formation by plasma membrane fusion →	+0.116	+1.624	<.001	.001	3	8
LIVER	Cellular respiration →	+0.095	+1.473	.003	.007	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,953 associations by consensus.

Aerobic respiration by SLC7A8 expression — LIVER

Explore this box plot interactively →