SLC7A6OS

Across TCGA pan-cancer cohorts, SLC7A6OS mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SLC7A6OS data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SLC7A6OS mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC7A6OS expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

HNSC, LUAD, and LSCC are the cancer types where SLC7A6OS mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.895	0.234	.001	75	view →
LUAD	OS	Tertile	II,III,IV	0.550	1.000	.017	10	view →
LSCC	DFS	Quartile	II,III,IV	0.746	0.952	.027	2	view →
CCRCC	OS	Quartile	III,IV	0.253	0.693	.022	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SLC7A6OS–HNSC (DFS)

Open the HNSC breakdown →