SLC7A6

Across TCGA patient cohorts, SLC7A6 mutation is significantly associated with the RNA expression of many other genes, with 903 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC7A6-associated genes across cancer lineages are RNA5SP419, MTND3P21, and MIR6885. Each is linked with SLC7A6 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC7A6-to-partner and partner-to-SLC7A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP419 grouped by SLC7A6-low versus SLC7A6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A6→partner) and Y-score (partner→SLC7A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP419 →	+0.436	+1.787	<.001	.002	3	2
LUSC	MTND3P21 →	+0.161	+5.273	<.001	.006	3	2
BRCA	MIR6885 →	+0.473	+5.070	.003	.008	3	1
SKCM	SRP72P1 →	+0.242	+4.009	<.001	.003	3	1
BLCA	OR6C74 →	+0.027	+4.899	.002	.005	3	1
BLCA	RNU1-83P →	+0.329	+4.588	.007	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 903 associations by consensus.

RNA5SP419 by SLC7A6 expression — UCEC

Explore this box plot interactively →