SLC7A6

Across TCGA cell cohorts, SLC7A6 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. KIDNEY shows the largest number of these associations.

The most reproducible SLC7A6-associated genes across cancer lineages are UGT2B28, TGIF2LX, and NTSR2. Each is linked with SLC7A6 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC7A6-to-partner and partner-to-SLC7A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UGT2B28 grouped by SLC7A6-low versus SLC7A6-high in KIDNEY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A6→partner) and Y-score (partner→SLC7A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	UGT2B28 →	+0.013	+5.000	<.001	.005	3	1
KIDNEY	TGIF2LX →	+0.053	+5.000	<.001	.005	3	1
KIDNEY	NTSR2 →	+0.053	+5.000	<.001	.005	3	1
KIDNEY	DUSP21 →	+0.036	+5.000	<.001	.005	3	1
KIDNEY	MAS1L →	+0.020	+5.000	<.001	.005	3	1
KIDNEY	POTEM →	+0.069	+5.000	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

UGT2B28 by SLC7A6 expression — KIDNEY

Explore this box plot interactively →