SLC7A3

Across TCGA patient cohorts, SLC7A3 protein abundance is significantly associated with the RNA expression of many other genes, with 1,530 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLC7A3-associated genes across cancer lineages are SLC16A8, TMED8, and CHGA. Each is linked with SLC7A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC7A3-to-partner and partner-to-SLC7A3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC7A3 versus SLC16A8 in GBM, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A3→partner) and Y-score (partner→SLC7A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SLC16A8 →	+0.684	+0.520	.002	<.001	3	1
GBM	TMED8 →	+0.359	+0.437	.002	.002	3	1
GBM	CHGA →	+1.976	+0.499	<.001	<.001	3	1
GBM	SLC8A3 →	+1.496	+0.604	<.001	<.001	3	1
GBM	DICER1 →	+0.388	+0.423	.001	.005	3	1
GBM	RPS6KA5 →	+0.885	+0.758	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,530 associations by consensus.

SLC7A3 vs SLC16A8 — GBM

Explore this scatter interactively →