SLC7A2

Across TCGA patient cohorts, SLC7A2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,925 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SLC7A2-associated genes across cancer lineages are ATP8B1, PDE3B, and SLAMF8. Each is linked with SLC7A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC7A2-to-partner and partner-to-SLC7A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC7A2 versus ATP8B1 in OV, with a Pearson correlation of 0.76.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A2→partner) and Y-score (partner→SLC7A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ATP8B1 →	+0.920	+1.281	<.001	<.001	3	3
HNSC	PDE3B →	+1.005	+0.748	.006	.007	3	3
LUAD	SLAMF8 →	-0.908	-1.265	<.001	<.001	3	3
UCEC	SLC7A2-IT1 →	+2.835	+1.798	<.001	<.001	3	3
OV	PBX4 →	-1.365	-1.522	<.001	.003	3	2
OV	MPP2 →	-1.027	-1.214	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,925 associations by consensus.

SLC7A2 vs ATP8B1 — OV

Explore this scatter interactively →