SLC7A2-IT1

Across TCGA pan-cancer cohorts, SLC7A2-IT1 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated SLC7A2-IT1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher SLC7A2-IT1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SLC7A2-IT1 expression acts as an unfavorable survival marker, although some lineages such as LGG and LAML show a favorable association.

ACC, KIRC, and KIRP are the cancer types where SLC7A2-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.176	0.666	<.001	72	view →
KIRC	OS	Quartile	All	0.482	0.690	<.001	70	view →
KIRP	DFS	Tertile	II,III,IV	0.160	0.793	<.001	54	view →
SKCM	OS	Tertile	II,III,IV	0.177	0.415	.003	36	view →
LGG	DFS	Quartile	All	0.767	0.356	.001	31	view →
CESC	DFS	Tertile	II,III,IV	0.507	0.817	<.001	30	view →
CHOL	OS	Tertile	II,III,IV	0.289	0.794	.005	27	view →
LAML	DFS	Tertile	All	0.607	0.287	.008	26	view →
BRCA	DFS	Tertile	III,IV	0.937	0.835	.002	25	view →
STAD	OS	Tertile	II,III,IV	0.549	0.758	.013	15	view →
READ	DFS	Tertile	IV	0.095	0.697	.014	9	view →
UCEC	DFS	Tertile	All	0.752	0.849	.033	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

SLC7A2-IT1–ACC (OS)

Open the ACC breakdown →