SLC7A2-IT1

Across TCGA pan-cancer cohorts, SLC7A2-IT1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of SLC7A2-IT1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where SLC7A2-IT1 RNA is repressed in tumor relative to normal tissue. In most cancer types SLC7A2-IT1 is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.

KICH, UCEC, and BRCA are the cancer types where SLC7A2-IT1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC7A2-IT1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−0.147	.002	6	view →
UCEC	All	All	−0.311	.003	4	view →
BRCA	Female	II,III,IV	+0.217	<.001	4	view →
KIRC	All	All	−0.055	.004	4	view →
CHOL	All	All	−0.275	.001	3	view →
LUSC	Female	All	−0.193	.004	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

SLC7A2-IT1–KICH

Open the KICH breakdown →