SLC7A14

Across TCGA patient cohorts, SLC7A14 mutation is significantly associated with the RNA expression of many other genes, with 3,637 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC7A14-associated genes across cancer lineages are TSPY26P, MIR6870, and RNA5SP412. Each is linked with SLC7A14 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC7A14-to-partner and partner-to-SLC7A14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSPY26P grouped by SLC7A14-low versus SLC7A14-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A14→partner) and Y-score (partner→SLC7A14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TSPY26P →	-0.484	-1.536	.008	.002	3	4
READ	MIR6870 →	+0.680	+3.695	<.001	.003	3	3
UCEC	RNA5SP412 →	+0.504	+1.967	<.001	<.001	3	3
UCEC	SOCS6 →	+0.413	+1.747	.002	<.001	3	3
UCEC	SCN4B →	-0.305	-1.837	.007	.007	3	3
UCEC	RAD51 →	+0.711	+2.203	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,637 associations by consensus.

TSPY26P by SLC7A14 expression — UCEC

Explore this box plot interactively →