SLC7A14

Across TCGA cell cohorts, SLC7A14 RNA expression is significantly associated with the go_rna of many other GO terms, with 646 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SLC7A14-associated GO terms across cancer lineages are Positive regulation of cytoplasmic translation, Regulation of syncytium formation by plasma membrane fusion, and Protein modification by small protein removal. Each is linked with SLC7A14 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLC7A14-to-partner and partner-to-SLC7A14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cytoplasmic translation grouped by SLC7A14-low versus SLC7A14-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A14→partner) and Y-score (partner→SLC7A14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of cytoplasmic translation →	+0.105	+2.426	.001	<.001	3	5
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.107	+2.310	<.001	.001	3	5
LARGE_INTESTINE	Protein modification by small protein removal →	+0.029	+0.013	.001	.008	3	5
LARGE_INTESTINE	Response to gamma radiation →	+0.079	+0.007	<.001	.008	3	4
LARGE_INTESTINE	Heterochromatin formation →	+0.045	+0.007	<.001	.004	3	4
LARGE_INTESTINE	Protein localization to Golgi apparatus →	+0.058	+0.007	.002	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 646 associations by consensus.

Positive regulation of cytoplasmic translation by SLC7A14 expression — LUNG_SCLC

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