SLC7A14

Across TCGA cell cohorts, SLC7A14 mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SLC7A14-associated genes across cancer lineages are MSGN1, GHRH, and NLRP8. Each is linked with SLC7A14 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC7A14-to-partner and partner-to-SLC7A14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MSGN1 grouped by SLC7A14-low versus SLC7A14-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A14→partner) and Y-score (partner→SLC7A14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	MSGN1 →	+0.038	+3.700	<.001	.009	3	2
OESOPHAGUS	GHRH →	+0.060	+4.906	<.001	.006	3	1
OESOPHAGUS	NLRP8 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	KLHL34 →	+0.013	+4.906	<.001	.006	3	1
OESOPHAGUS	PPIAL4F →	+0.060	+4.906	<.001	.006	3	1
BLOOD_Leukemia	GSG1L2 →	+0.034	+4.384	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

MSGN1 by SLC7A14 expression — SKIN

Explore this box plot interactively →