SLC7A13

Across TCGA patient cohorts, SLC7A13 mutation is significantly associated with the RNA expression of many other genes, with 1,617 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC7A13-associated genes across cancer lineages are RNA5SP419, NHEJ1, and ZFPL1. Each is linked with SLC7A13 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC7A13-to-partner and partner-to-SLC7A13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP419 grouped by SLC7A13-low versus SLC7A13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A13→partner) and Y-score (partner→SLC7A13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP419 →	+0.639	+1.999	<.001	.001	3	3
SKCM	NHEJ1 →	+0.239	+2.682	.002	<.001	3	3
LUSC	ZFPL1 →	+0.322	+3.682	.002	.001	3	3
UCEC	GORASP2 →	+0.365	+1.872	.002	.004	3	3
UCEC	CPAMD8 →	-1.146	-3.161	<.001	<.001	3	3
SCLC	APOC3 →	+0.344	+4.329	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,617 associations by consensus.

RNA5SP419 by SLC7A13 expression — UCEC

Explore this box plot interactively →