SLC7A13

Across TCGA pan-cancer cohorts, SLC7A13 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated SLC7A13 data layer compared with 7 for mutation status.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher SLC7A13 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC7A13 expression acts as an unfavorable survival marker, although some lineages such as KIRC and BRCA show a favorable association.

READ, KIRC, and UCS are the cancer types where SLC7A13 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Tertile	All	0.152	0.547	.016	54	view →
KIRC	DFS	Median	All	0.848	0.758	<.001	47	view →
UCS	OS	Tertile	III,IV	0.052	0.612	<.001	36	view →
BRCA	OS	Tertile	IV	0.820	0.171	.009	33	view →
LUSC	DFS	Tertile	II,III,IV	0.866	0.406	.006	30	view →
KIRP	DFS	Median	II,III,IV	0.798	0.580	.023	21	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	20	view →
SKCM	DFS	Tertile	IV	0.036	0.433	<.001	18	view →
THCA	OS	Tertile	All	0.917	0.989	.011	18	view →
BLCA	DFS	Quartile	All	0.617	0.267	.014	14	view →
LIHC	DFS	Quartile	All	0.533	0.287	.002	13	view →
STAD	DFS	Median	II,III,IV	0.660	0.477	.010	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

SLC7A13–READ (DFS)

Open the READ breakdown →