SLC7A13

Across TCGA cell cohorts, SLC7A13 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SLC7A13-associated genes across cancer lineages are NPY, RAX2, and USP17L7. Each is linked with SLC7A13 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC7A13-to-partner and partner-to-SLC7A13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NPY grouped by SLC7A13-low versus SLC7A13-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A13→partner) and Y-score (partner→SLC7A13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	NPY →	+0.077	+3.459	<.001	.009	3	1
LARGE_INTESTINE	RAX2 →	+0.077	+3.196	<.001	.007	3	1
LARGE_INTESTINE	USP17L7 →	+0.080	+3.691	<.001	.009	3	1
LARGE_INTESTINE	OR4A47 →	+0.015	+4.022	<.001	.006	3	1
OVARY	CCDC182 →	+0.073	+4.700	<.001	.002	3	1
OVARY	ARMH2 →	+0.052	+4.228	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

NPY by SLC7A13 expression — LARGE_INTESTINE

Explore this box plot interactively →