SLC7A11

Across TCGA patient cohorts, SLC7A11 protein abundance is significantly associated with the protein abundance of many other proteins, with 9,682 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLC7A11-associated proteins across cancer lineages are PTPN7, RAB6B, and RASSF5. Each is linked with SLC7A11 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC7A11-to-partner and partner-to-SLC7A11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC7A11 versus PTPN7 in LSCC, with a Pearson correlation of -0.36.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A11→partner) and Y-score (partner→SLC7A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PTPN7 →	-0.438	-1.470	<.001	<.001	3	3
LSCC	RAB6B →	+0.902	+0.977	<.001	<.001	3	3
LSCC	RASSF5 →	-0.401	-1.398	<.001	.001	3	3
HNSC	BTK →	-0.498	-1.187	<.001	.001	3	3
HNSC	COA3 →	+0.476	+1.991	<.001	<.001	3	3
LSCC	DOCK8_S451 →	-0.767	-1.642	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,682 associations by consensus.

SLC7A11 vs PTPN7 — LSCC

Explore this scatter interactively →