SLC7A11-AS1

Across TCGA pan-cancer cohorts, SLC7A11-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated SLC7A11-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher SLC7A11-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC7A11-AS1 expression acts as an unfavorable survival marker, although some lineages such as READ and BRCA show a favorable association.

ACC, KICH, and THCA are the cancer types where SLC7A11-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.389	0.712	<.001	111	view →
KICH	DFS	Quartile	All	0.732	1.000	<.001	98	view →
THCA	OS	Tertile	All	0.942	1.000	<.001	92	view →
LIHC	DFS	Median	All	0.463	0.599	<.001	78	view →
KIRP	DFS	Median	All	0.849	0.971	<.001	61	view →
LGG	DFS	Tertile	All	0.744	0.868	<.001	38	view →
LAML	DFS	Tertile	All	0.205	0.646	<.001	34	view →
LUAD	DFS	Tertile	All	0.712	0.825	.001	30	view →
HNSC	OS	Median	All	0.226	0.494	.005	25	view →
ESCA	DFS	Median	III,IV	0.307	0.578	.001	25	view →
UVM	OS	Tertile	All	0.287	0.732	<.001	24	view →
COAD	OS	Quartile	All	0.769	0.906	.019	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

SLC7A11-AS1–ACC (DFS)

Open the ACC breakdown →