SLC7A11-AS1

Across TCGA pan-cancer cohorts, SLC7A11-AS1 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of SLC7A11-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SLC7A11-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SLC7A11-AS1 is over-expressed in tumor.

KIRC, HNSC, and COAD are the cancer types where SLC7A11-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC7A11-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+0.013	<.001	6	view →
HNSC	All	All	+0.191	.006	5	view →
COAD	All	All	+0.120	.002	5	view →
LIHC	All	All	+0.044	.001	5	view →
PAAD	All	All	+0.162	<.001	4	view →
READ	All	II,III,IV	+0.122	.001	4	view →
BRCA	All	All	+0.073	.003	4	view →
KICH	All	All	+0.055	.003	4	view →
LUSC	Male	All	+0.302	.010	3	view →
KIRP	All	II,III,IV	+0.155	.023	3	view →
STAD	All	All	+0.186	.025	2	view →
PRAD	All	All	+0.114	.009	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

SLC7A11-AS1–KIRC

Open the KIRC breakdown →