Across TCGA patient cohorts, SLC6A9 mutation is significantly associated with the RNA expression of many other genes, with 3,273 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC6A9-associated genes across cancer lineages are TAF9, CENPU, and SKA1. Each is linked with SLC6A9 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC6A9-to-partner and partner-to-SLC6A9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A9→partner) and Y-score (partner→SLC6A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TAF9 →	+0.623	+2.222	<.001	<.001	3	3
UCEC	CENPU →	+0.580	+2.949	.001	<.001	3	3
UCEC	SKA1 →	+0.771	+2.233	<.001	<.001	3	3
UCEC	PEX13 →	+0.353	+1.939	.004	.008	3	3
UCEC	POC1A →	+0.460	+2.408	.004	<.001	3	3
UCEC	STARD4 →	+0.535	+2.016	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,273 associations by consensus.

Exploration

SLC6A9 survival (RNA) · tumor vs normal (RNA) · all SLC6A9 data types