Across TCGA patient cohorts, SLC6A9 mutation is significantly associated with the total protein of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC6A9-associated genes across cancer lineages are MEK1, Notch1, and p70-S6K. Each is linked with SLC6A9 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC6A9-to-partner and partner-to-SLC6A9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A9→partner) and Y-score (partner→SLC6A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.346	+2.169	.004	.003	3	3
UCEC	Notch1 →	+0.148	+2.013	.001	.016	3	2
UCEC	p70-S6K →	+0.156	+1.901	.015	.001	3	2
UCEC	PCNA →	+0.219	+2.087	.002	.005	3	2
UCEC	Rictor_pT1135 →	-0.110	-2.087	.001	.005	3	2
UCEC	14-3-3_beta →	-0.078	-1.973	.020	.029	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

Exploration

SLC6A9 survival (RNA) · tumor vs normal (RNA) · all SLC6A9 data types