Across TCGA cell cohorts, SLC6A9 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SLC6A9-associated genes across cancer lineages are KRTAP13-2, OR6M1, and GUCA2A. Each is linked with SLC6A9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC6A9-to-partner and partner-to-SLC6A9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A9→partner) and Y-score (partner→SLC6A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	KRTAP13-2 →	+0.032	+5.029	<.001	.006	3	2
BLOOD_Leukemia	OR6M1 →	+0.024	+4.539	<.001	.007	3	1
BLOOD_Leukemia	GUCA2A →	+0.039	+4.969	<.001	.003	3	1
BLOOD_Leukemia	KRTAP7-1 →	+0.071	+4.539	<.001	.007	3	1
SKIN	OR2B2 →	+0.027	+4.684	<.001	.002	3	1
SKIN	EDDM3B →	+0.029	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

SLC6A9 survival (RNA) · tumor vs normal (RNA) · all SLC6A9 data types