SLC6A20

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC6A20 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC6A20-associated genes across cancer lineages are ASZ1, ADAMTSL3, and TNNI1. Each is linked with SLC6A20 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC6A20-to-partner and partner-to-SLC6A20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASZ1 grouped by SLC6A20-low versus SLC6A20-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A20→partner) and Y-score (partner→SLC6A20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaASZ1 →+0.087+2.982.002.00731
BLOOD_LeukemiaADAMTSL3 →+0.130+3.474<.001.00731
BLOOD_LeukemiaTNNI1 →+0.415+3.607<.001.00431
BLOOD_LeukemiaFCRL3 →+0.847+4.038<.001.00131
BLOOD_LeukemiaRNASE7 →+0.037+3.579.004.00731
BLOOD_LeukemiaMT1B →+0.082+4.247<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

ASZ1 by SLC6A20 expression — BLOOD_Leukemia

Box plot of ASZ1 in SLC6A20-low vs SLC6A20-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration