SLC6A18

Across TCGA patient cohorts, SLC6A18 mutation is significantly associated with the RNA expression of many other genes, with 2,288 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC6A18-associated genes across cancer lineages are BCCIP, INTS2, and LRRC59. Each is linked with SLC6A18 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC6A18-to-partner and partner-to-SLC6A18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BCCIP grouped by SLC6A18-low versus SLC6A18-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A18→partner) and Y-score (partner→SLC6A18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	BCCIP →	+0.426	+2.954	.006	<.001	3	3
SKCM	INTS2 →	+0.526	+2.725	.003	.002	3	3
UCEC	LRRC59 →	+0.486	+1.936	.001	.003	3	3
SKCM	NOL11 →	+0.444	+3.713	.008	<.001	3	3
UCEC	TTC5 →	+0.374	+2.332	.004	<.001	3	3
UCEC	PRR11 →	+0.609	+1.936	.004	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,288 associations by consensus.

BCCIP by SLC6A18 expression — SKCM

Explore this box plot interactively →