SLC6A18

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC6A18 RNA expression is significantly associated with the go_rna of many other GO terms, with 803 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SLC6A18-associated GO terms across cancer lineages are Cardiolipin metabolic process, Mitotic cell cycle phase transition, and Positive regulation of protein maturation. Each is linked with SLC6A18 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC6A18-to-partner and partner-to-SLC6A18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cardiolipin metabolic process grouped by SLC6A18-low versus SLC6A18-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A18→partner) and Y-score (partner→SLC6A18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASCardiolipin metabolic process →+0.077+0.038<.001.00634
BONEMitotic cell cycle phase transition →+0.073+0.035.002.00334
BONEPositive regulation of protein maturation →-0.167-0.033.001.00433
BONERegulation of double-strand break repair →+0.066+0.036.001.00233
BONEMitotic DNA integrity checkpoint signaling →+0.090+0.046<.001.00433
BONECell cycle G1/S phase transition →+0.071+0.041.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 803 associations by consensus.

Cardiolipin metabolic process by SLC6A18 expression — PANCREAS

Box plot of Cardiolipin metabolic process in SLC6A18-low vs SLC6A18-high samples in PANCREAS.

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Exploration