SLC6A18

Across TCGA cell cohorts, SLC6A18 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SLC6A18-associated genes across cancer lineages are FUT5, RHOXF2, and OR13D1. Each is linked with SLC6A18 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC6A18-to-partner and partner-to-SLC6A18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FUT5 grouped by SLC6A18-low versus SLC6A18-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A18→partner) and Y-score (partner→SLC6A18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FUT5 →	+0.018	+2.657	.002	.007	3	1
LARGE_INTESTINE	RHOXF2 →	+0.041	+2.807	<.001	.006	3	1
LARGE_INTESTINE	OR13D1 →	+0.029	+2.882	<.001	.005	3	1
BREAST	MYH8 →	+0.015	+3.781	<.001	.009	3	1
BREAST	CFC1B →	+0.003	+3.781	<.001	.009	3	1
BREAST	TGM6 →	+0.023	+3.727	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

FUT5 by SLC6A18 expression — LARGE_INTESTINE

Explore this box plot interactively →