Across TCGA patient cohorts, SLC6A17 mutation is significantly associated with the total protein of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC6A17-associated genes across cancer lineages are ATM, Caspase-7-cleavedD198, and EGFR_pY1068. Each is linked with SLC6A17 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC6A17-to-partner and partner-to-SLC6A17 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A17→partner) and Y-score (partner→SLC6A17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ATM →	-0.615	-3.450	<.001	.005	3	3
UCEC	Caspase-7-cleavedD198 →	+0.594	+2.522	.002	<.001	3	3
UCEC	EGFR_pY1068 →	-0.206	-2.263	.012	<.001	3	2
COAD	ASNS →	+0.699	+3.169	<.001	.018	3	2
UCEC	4E-BP1 →	+0.244	+3.029	.006	<.001	3	2
COAD	PKC-b-II_pS660 →	-0.488	-3.321	.002	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

Exploration

SLC6A17 survival (RNA) · tumor vs normal (RNA) · all SLC6A17 data types