Across TCGA cell cohorts, SLC6A17 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible SLC6A17-associated genes across cancer lineages are TPPP2, CST9L, and PLA2G2D. Each is linked with SLC6A17 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC6A17-to-partner and partner-to-SLC6A17 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A17→partner) and Y-score (partner→SLC6A17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	TPPP2 →	+0.089	+4.421	<.001	.004	3	2
CNS	CST9L →	+0.010	+4.035	<.001	.006	3	1
CNS	PLA2G2D →	+0.342	+3.103	<.001	.005	3	1
CNS	PYHIN1 →	+0.134	+2.906	.005	.009	3	1
CNS	SPATA48 →	+0.015	+4.035	<.001	.006	3	1
CNS	SPATA31A5 →	+0.018	+3.906	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

SLC6A17 survival (RNA) · tumor vs normal (RNA) · all SLC6A17 data types