SLC6A16

Across TCGA cell cohorts, SLC6A16 protein abundance is significantly associated with the RNA expression of many other genes, with 2,550 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SLC6A16-associated genes across cancer lineages are YPEL3, PNPO, and TMEM164. Each is linked with SLC6A16 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLC6A16-to-partner and partner-to-SLC6A16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC6A16 versus YPEL3 in LUNG_SCLC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A16→partner) and Y-score (partner→SLC6A16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	YPEL3 →	+1.421	+0.769	.005	.008	3	5
BLOOD_Lymphoma	PNPO →	-0.578	-0.665	.003	.003	3	4
STOMACH	TMEM164 →	-1.284	-1.314	<.001	.005	3	4
UPPER_AERODIGESTIVE_TRACT	HMSD →	+1.102	+1.782	.003	.001	3	4
LIVER	HAS3 →	-3.114	-1.314	<.001	.007	3	4
PANCREAS	PCCB →	-0.832	-1.565	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,550 associations by consensus.

SLC6A16 vs YPEL3 — LUNG_SCLC

Explore this scatter interactively →