SLC6A14

Across TCGA patient cohorts, SLC6A14 mutation is significantly associated with the RNA expression of many other genes, with 4,597 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC6A14-associated genes across cancer lineages are OR2J3, RNA5SP412, and FAM204A. Each is linked with SLC6A14 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC6A14-to-partner and partner-to-SLC6A14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2J3 grouped by SLC6A14-low versus SLC6A14-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A14→partner) and Y-score (partner→SLC6A14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	OR2J3 →	+0.010	+2.444	.002	.006	3	3
UCEC	RNA5SP412 →	+0.454	+1.588	<.001	.003	3	3
SKCM	FAM204A →	+0.396	+1.822	.001	.001	3	2
UCEC	PSMC3 →	+0.317	+1.617	.001	.001	3	2
UCEC	ZFYVE19 →	+0.444	+2.094	<.001	<.001	3	2
UCEC	TRABD →	+0.406	+2.354	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,597 associations by consensus.

OR2J3 by SLC6A14 expression — SKCM

Explore this box plot interactively →