SLC6A13

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC6A13 mutation is significantly associated with the RNA expression of many other genes, with 3,056 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC6A13-associated genes across cancer lineages are RNU6-528P, OR4C9P, and HSBP1P2. Each is linked with SLC6A13 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC6A13-to-partner and partner-to-SLC6A13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-528P grouped by SLC6A13-low versus SLC6A13-high in KIRP.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A13→partner) and Y-score (partner→SLC6A13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
KIRPRNU6-528P →+0.170+4.943<.001.00333
SKCMOR4C9P →+0.016+3.163<.001.00333
SKCMHSBP1P2 →+0.130+1.360<.001.00733
UCECRNF34 →+0.294+2.145.002<.00133
SKCMRNA5SP64 →+0.061+2.341.002.00733
SKCMOR10R1P →+0.018+2.122<.001.00333
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,056 associations by consensus.

RNU6-528P by SLC6A13 expression — KIRP

Box plot of RNU6-528P in SLC6A13-low vs SLC6A13-high samples in KIRP.

Explore this box plot interactively →

Exploration