SLC6A13

Across TCGA pan-cancer cohorts, SLC6A13 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated SLC6A13 data layer compared with 7 for mutation status and 2 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SLC6A13 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC6A13 expression acts as an unfavorable survival marker, although some lineages such as KIRC and KIRP show a favorable association.

KIRC, KIRP, and UCEC are the cancer types where SLC6A13 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.722	0.534	<.001	149	view →
KIRP	OS	Quartile	All	0.950	0.788	.002	113	view →
UCEC	OS	Median	All	0.574	0.778	.002	70	view →
LUAD	DFS	Median	IV	0.374	0.817	.001	42	view →
UCS	DFS	Median	II,III,IV	0.594	0.282	.007	40	view →
PAAD	DFS	Quartile	All	0.479	0.185	.002	36	view →
READ	DFS	Tertile	III,IV	0.566	0.191	.001	31	view →
PCPG	DFS	Tertile	All	0.916	0.592	.007	22	view →
DLBC	DFS	Quartile	All	0.492	1.000	.005	20	view →
TGCT	DFS	Quartile	All	0.497	0.784	.013	12	view →
BLCA	DFS	Median	All	0.677	0.500	.025	12	view →
SARC	DFS	Quartile	All	0.671	0.359	.003	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

SLC6A13–KIRC (DFS)

Open the KIRC breakdown →