SLC6A13

Across TCGA cell cohorts, SLC6A13 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SLC6A13-associated genes across cancer lineages are CLEC4C, ASPN, and TPD52L3. Each is linked with SLC6A13 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC6A13-to-partner and partner-to-SLC6A13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLEC4C grouped by SLC6A13-low versus SLC6A13-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A13→partner) and Y-score (partner→SLC6A13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	CLEC4C →	+0.022	+5.169	<.001	.005	3	1
LARGE_INTESTINE	ASPN →	+0.061	+3.378	<.001	.006	3	1
SKIN	TPD52L3 →	+0.002	+3.700	<.001	.009	3	1
SKIN	OR52W1 →	+0.059	+4.000	<.001	.004	3	1
LUNG_SCLC	IL36A →	+0.026	+5.643	<.001	.002	3	1
LUNG_SCLC	OR7G3 →	+0.063	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

CLEC4C by SLC6A13 expression — BREAST

Explore this box plot interactively →