SLC6A12

Across TCGA patient cohorts, SLC6A12 protein abundance is significantly associated with the RNA expression of many other genes, with 2,242 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SLC6A12-associated genes across cancer lineages are LRP11, PIAS3, and ADCY1. Each is linked with SLC6A12 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC6A12-to-partner and partner-to-SLC6A12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC6A12 versus LRP11 in UCEC, with a Pearson correlation of -0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A12→partner) and Y-score (partner→SLC6A12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LRP11 →	-0.721	-1.031	.005	<.001	3	2
UCEC	PIAS3 →	-1.014	-1.112	.008	.006	3	2
UCEC	ADCY1 →	-3.239	-1.199	.001	.001	3	2
LSCC	TRBJ2-5 →	+1.794	+0.472	.001	.003	3	2
UCEC	PMM1 →	-1.644	-1.175	.004	.001	3	1
UCEC	MTMR8 →	-2.167	-1.044	.004	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,242 associations by consensus.

SLC6A12 vs LRP11 — UCEC

Explore this scatter interactively →