SLC6A12

Across TCGA cell cohorts, SLC6A12 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,656 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SLC6A12-associated GO terms across cancer lineages are Amino acid neurotransmitter reuptake, Gamma-aminobutyric acid reuptake, and Glycine betaine transport. Each is linked with SLC6A12 in more than 11 cancer types. Because this analysis shows association rather than direction, both SLC6A12-to-partner and partner-to-SLC6A12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Amino acid neurotransmitter reuptake grouped by SLC6A12-low versus SLC6A12-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A12→partner) and Y-score (partner→SLC6A12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Amino acid neurotransmitter reuptake →	+1.392	+2.395	.001	.001	3	12
LIVER	Gamma-aminobutyric acid reuptake →	+1.392	+2.395	.001	.001	3	12
BLOOD_Leukemia	Glycine betaine transport →	-0.159	-0.736	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Post-translational protein targeting to membrane, translocation →	+0.111	+0.629	<.001	<.001	3	11
LARGE_INTESTINE	Microtubule bundle formation →	-0.039	-0.492	<.001	<.001	3	8
CNS	Negative regulation of respiratory burst involved in inflammatory response →	+0.059	+0.620	.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,656 associations by consensus.

Amino acid neurotransmitter reuptake by SLC6A12 expression — LIVER

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