SLC6A11

Across TCGA cell cohorts, SLC6A11 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,899 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible SLC6A11-associated GO terms across cancer lineages are Amino acid neurotransmitter reuptake, Gamma-aminobutyric acid reuptake, and Negative regulation of mRNA metabolic process. Each is linked with SLC6A11 in more than 9 cancer types. Because this analysis shows association rather than direction, both SLC6A11-to-partner and partner-to-SLC6A11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Amino acid neurotransmitter reuptake grouped by SLC6A11-low versus SLC6A11-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A11→partner) and Y-score (partner→SLC6A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Amino acid neurotransmitter reuptake →	+0.828	+1.820	<.001	<.001	3	10
BREAST	Gamma-aminobutyric acid reuptake →	+0.828	+1.820	<.001	<.001	3	10
URINARY_TRACT	Negative regulation of mRNA metabolic process →	+0.076	+1.943	.002	<.001	3	10
LIVER	Regulation of translational fidelity →	+0.130	+2.222	.001	<.001	3	6
URINARY_TRACT	Negative regulation of mRNA catabolic process →	+0.074	+1.672	<.001	<.001	3	6
OESOPHAGUS	Negative regulation of RNA catabolic process →	+0.062	+1.477	.001	.004	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,899 associations by consensus.

Amino acid neurotransmitter reuptake by SLC6A11 expression — BREAST

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