SLC66A1

Across TCGA cell cohorts, SLC66A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,438 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC66A1-associated GO terms across cancer lineages are L-histidine transmembrane transport, Endosomal transport, and Positive regulation of type 2 mitophagy. Each is linked with SLC66A1 in more than 12 cancer types. Because this analysis shows association rather than direction, both SLC66A1-to-partner and partner-to-SLC66A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, L-histidine transmembrane transport grouped by SLC66A1-low versus SLC66A1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC66A1→partner) and Y-score (partner→SLC66A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	L-histidine transmembrane transport →	+0.178	+1.085	<.001	<.001	3	13
SKIN	Endosomal transport →	+0.052	+0.942	<.001	<.001	3	13
PANCREAS	Positive regulation of type 2 mitophagy →	+0.123	+0.531	<.001	.001	3	13
STOMACH	Vacuole organization →	+0.057	+0.970	<.001	.001	3	13
PANCREAS	Regulation of autophagy of mitochondrion →	+0.094	+0.643	<.001	.001	3	12
BONE	Positive regulation of autophagy of mitochondrion →	+0.141	+0.850	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,438 associations by consensus.

L-histidine transmembrane transport by SLC66A1 expression — LUNG_SCLC

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