SLC5A9

Across TCGA patient cohorts, SLC5A9 mutation is significantly associated with the total protein of many other genes, with 45 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC5A9-associated genes across cancer lineages are ERK2, EGFR_pY1068, and eIF4E. Each is linked with SLC5A9 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC5A9-to-partner and partner-to-SLC5A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERK2 grouped by SLC5A9-low versus SLC5A9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A9→partner) and Y-score (partner→SLC5A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.204	+1.523	<.001	.008	3	3
UCEC	EGFR_pY1068 →	-0.206	-1.777	.010	.002	3	2
UCEC	eIF4E →	+0.171	+1.523	.011	.008	3	2
UCEC	FoxM1 →	+0.186	+2.058	.024	<.001	3	2
UCEC	MEK1 →	+0.528	+2.754	<.001	<.001	3	2
UCEC	PCNA →	+0.256	+2.807	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

ERK2 by SLC5A9 expression — UCEC

Explore this box plot interactively →