SLC5A5

Across TCGA patient cohorts, SLC5A5 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,073 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible SLC5A5-associated GO terms across cancer lineages are Negative regulation of kinase activity, Apoptotic mitochondrial changes, and Monosaccharide metabolic process. Each is linked with SLC5A5 in more than 17 cancer types. Because this analysis shows association rather than direction, both SLC5A5-to-partner and partner-to-SLC5A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of kinase activity grouped by SLC5A5-low versus SLC5A5-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A5→partner) and Y-score (partner→SLC5A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Negative regulation of kinase activity →	+0.055	+0.544	.002	<.001	2	18
STAD	Apoptotic mitochondrial changes →	+0.057	+0.841	<.001	<.001	3	17
STAD	Monosaccharide metabolic process →	+0.051	+0.795	<.001	<.001	3	17
SCLC	Lysosomal transport →	+0.086	+0.596	<.001	.002	3	17
ESCA	ER-nucleus signaling pathway →	+0.082	+0.930	<.001	<.001	3	16
ESCA	Vacuolar transport →	+0.055	+0.829	<.001	.004	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,073 associations by consensus.

Negative regulation of kinase activity by SLC5A5 expression — SCLC

Explore this box plot interactively →