SLC5A4

Across TCGA patient cohorts, SLC5A4 protein abundance is significantly associated with the RNA expression of many other genes, with 623 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC5A4-associated genes across cancer lineages are PPM1F, CRYBB2P1, and GGA1. Each is linked with SLC5A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC5A4-to-partner and partner-to-SLC5A4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC5A4 versus PPM1F in UCEC, with a Pearson correlation of -0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A4→partner) and Y-score (partner→SLC5A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PPM1F →	-0.610	-1.430	.002	.003	3	1
UCEC	CRYBB2P1 →	-1.251	-1.437	<.001	<.001	3	1
UCEC	GGA1 →	-0.728	-1.085	.003	<.001	3	1
UCEC	HIRA →	-0.649	-1.538	.004	<.001	3	1
UCEC	TRIOBP →	-0.894	-1.384	.007	.001	3	1
UCEC	FBXO7 →	-0.705	-1.368	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 623 associations by consensus.

SLC5A4 vs PPM1F — UCEC

Explore this scatter interactively →