SLC5A4

Across TCGA cell cohorts, SLC5A4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,313 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SLC5A4-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Regulation of myoblast fusion, and Cytoplasmic translation. Each is linked with SLC5A4 in more than 5 cancer types. Because this analysis shows association rather than direction, both SLC5A4-to-partner and partner-to-SLC5A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by SLC5A4-low versus SLC5A4-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A4→partner) and Y-score (partner→SLC5A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.146	+0.213	.002	.008	3	6
OESOPHAGUS	Regulation of myoblast fusion →	+0.127	+0.213	.002	.008	2	6
OESOPHAGUS	Cytoplasmic translation →	+0.116	+0.213	<.001	.008	3	5
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.118	+0.216	.002	.008	2	6
OESOPHAGUS	Nucleoside triphosphate metabolic process →	+0.124	+0.220	<.001	.005	2	6
BONE	Negative regulation of DNA-templated transcription initiation →	+0.109	+0.057	.004	.004	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,313 associations by consensus.

Negative regulation of myoblast fusion by SLC5A4 expression — OESOPHAGUS

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