SLC5A11

Across TCGA patient cohorts, SLC5A11 mutation is significantly associated with the RNA expression of many other genes, with 2,270 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC5A11-associated genes across cancer lineages are CENPU, RAD51, and CCM2L. Each is linked with SLC5A11 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC5A11-to-partner and partner-to-SLC5A11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CENPU grouped by SLC5A11-low versus SLC5A11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A11→partner) and Y-score (partner→SLC5A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CENPU →	+0.495	+1.847	.008	.008	3	3
UCEC	RAD51 →	+0.688	+2.389	<.001	<.001	3	3
UCEC	CCM2L →	-0.395	-2.121	.004	.003	3	3
SKCM	PDE1B →	-0.386	-2.788	.003	.003	3	3
SKCM	CKS2 →	+0.583	+1.893	.002	.001	3	3
SKCM	ADCY4 →	-0.402	-1.855	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,270 associations by consensus.

CENPU by SLC5A11 expression — UCEC

Explore this box plot interactively →