SLC5A11

Across TCGA cell cohorts, SLC5A11 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,089 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC5A11-associated GO terms across cancer lineages are Germ cell development, Regulation of proteasomal protein catabolic process, and Regulation of proteasomal ubiquitin-dependent protein catabolic process. Each is linked with SLC5A11 in more than 5 cancer types. Because this analysis shows association rather than direction, both SLC5A11-to-partner and partner-to-SLC5A11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Germ cell development grouped by SLC5A11-low versus SLC5A11-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A11→partner) and Y-score (partner→SLC5A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Germ cell development →	-0.045	-0.130	<.001	.005	3	6
LARGE_INTESTINE	Regulation of proteasomal protein catabolic process →	+0.045	+0.105	<.001	.001	3	6
LARGE_INTESTINE	Regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.051	+0.142	<.001	<.001	3	5
KIDNEY	Response to thyroxine →	+0.142	+0.373	.002	.001	3	5
KIDNEY	Cellular response to thyroid hormone stimulus →	+0.117	+0.355	.004	.007	3	5
UPPER_AERODIGESTIVE_TRACT	mRNA transcription by RNA polymerase II →	+0.067	+0.112	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,089 associations by consensus.

Germ cell development by SLC5A11 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →