SLC5A11

Across TCGA cell cohorts, SLC5A11 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLC5A11-associated genes across cancer lineages are OR10H5, TCP11X1, and PSKH2. Each is linked with SLC5A11 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC5A11-to-partner and partner-to-SLC5A11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10H5 grouped by SLC5A11-low versus SLC5A11-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A11→partner) and Y-score (partner→SLC5A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR10H5 →	+0.119	+5.209	<.001	.005	3	2
BLOOD_Lymphoma	TCP11X1 →	+0.006	+6.247	<.001	<.001	3	2
LUNG_NSCLC_LUAD	PSKH2 →	+0.012	+3.150	.001	.006	3	1
LUNG_NSCLC_LUAD	LCN9 →	+0.010	+3.681	<.001	.009	3	1
LUNG_NSCLC_LUAD	SPATA8 →	+0.066	+2.714	.003	.007	3	1
LUNG_NSCLC_LUAD	ZCCHC13 →	+0.008	+3.681	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

OR10H5 by SLC5A11 expression — BLOOD_Lymphoma

Explore this box plot interactively →