SLC5A10

Across TCGA patient cohorts, SLC5A10 mutation is significantly associated with the RNA expression of many other genes, with 3,369 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC5A10-associated genes across cancer lineages are MRPL34, HSBP1L1, and VN1R69P. Each is linked with SLC5A10 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC5A10-to-partner and partner-to-SLC5A10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRPL34 grouped by SLC5A10-low versus SLC5A10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A10→partner) and Y-score (partner→SLC5A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MRPL34 →	+0.415	+2.053	<.001	<.001	3	3
UCEC	HSBP1L1 →	+0.502	+4.010	<.001	<.001	3	3
SKCM	VN1R69P →	+0.115	+3.325	<.001	.004	3	3
UCEC	ZNHIT3 →	+0.463	+2.021	<.001	<.001	3	2
BLCA	VN1R93P →	+0.113	+4.883	<.001	.002	3	2
BLCA	REXO1L8P →	+0.059	+4.497	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,369 associations by consensus.

MRPL34 by SLC5A10 expression — UCEC

Explore this box plot interactively →