SLC5A1

Across TCGA patient cohorts, SLC5A1 mutation is significantly associated with the RNA expression of many other genes, with 3,833 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC5A1-associated genes across cancer lineages are BNIP3P41, RN7SL248P, and IFNA8. Each is linked with SLC5A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC5A1-to-partner and partner-to-SLC5A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BNIP3P41 grouped by SLC5A1-low versus SLC5A1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A1→partner) and Y-score (partner→SLC5A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BNIP3P41 →	+0.048	+5.786	<.001	.001	3	3
LIHC	RN7SL248P →	+0.094	+5.584	<.001	.001	3	2
BLCA	IFNA8 →	+0.040	+4.017	.001	.004	3	2
UCEC	DOC2B →	-0.847	-2.058	.001	<.001	3	2
UCEC	TAF9 →	+0.659	+2.058	<.001	<.001	3	2
UCEC	PSMB3 →	+0.329	+2.279	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,833 associations by consensus.

BNIP3P41 by SLC5A1 expression — BRCA

Explore this box plot interactively →