SLC52A2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC52A2 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC52A2-associated genes across cancer lineages are SSMEM1, FAM205A, and MYL7. Each is linked with SLC52A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC52A2-to-partner and partner-to-SLC52A2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC52A2→partner) and Y-score (partner→SLC52A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINESSMEM1 →+0.027+4.029<.001.00231
LARGE_INTESTINEFAM205A →+0.028+3.614<.001.00631
BLOOD_LeukemiaMYL7 →+0.105+4.339<.001.00231
BLOOD_LeukemiaHHLA1 →+0.009+3.551<.001.00931
BLOOD_LeukemiaSLC6A17 →+0.207+4.037<.001.00431
BLOOD_LeukemiaKHDC3L →+0.259+3.774<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration