SLC52A1

Across TCGA patient cohorts, SLC52A1 mutation is significantly associated with the RNA expression of many other genes, with 2,169 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC52A1-associated genes across cancer lineages are BTBD6, GPR53P, and LINC02639. Each is linked with SLC52A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC52A1-to-partner and partner-to-SLC52A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BTBD6 grouped by SLC52A1-low versus SLC52A1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC52A1→partner) and Y-score (partner→SLC52A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	BTBD6 →	+0.602	+3.328	.004	.005	3	2
SKCM	GPR53P →	+0.014	+4.049	<.001	.007	3	2
LUAD	LINC02639 →	+0.347	+4.379	<.001	.002	3	2
COAD	C1DP4 →	+0.160	+5.435	.002	.005	3	2
LUAD	RNA5SP521 →	+0.255	+4.303	<.001	.009	3	2
LUAD	SRSF3P2 →	+0.131	+4.076	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,169 associations by consensus.

BTBD6 by SLC52A1 expression — SKCM

Explore this box plot interactively →