Q-omics provides the consensus-scored GPR53P profile across patient tissues and cancer cell-line models. GPR53P expression is associated with patient survival in 11 of 34 cancer types, with the highest sampling consensus in BLCA. Additionally, GPR53P RNA expression shows 5,744 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight BLCA, and STAD as cancer lineages where GPR53P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes GPR53P survival associations across molecular data types. GPR53P RNA expression shows survival associations in the most cancer types (11). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

GPR53P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	11	BLCA (135)	view →

This table ranks reproducible GPR53P RNA expression–survival associations across cancer types. High GPR53P expression shows unfavorable associations in BLCA, UCEC, READ, LUAD, ACC and ESCA. The BLCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify BLCA as the clearest survival context for GPR53P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	All	0.172	0.522	<.001	135	view →
UCEC	DFS	Tertile	All	0.403	0.662	<.001	84	view →
READ	OS	Tertile	II,III,IV	0.083	0.919	<.001	72	view →
LUAD	DFS	Tertile	II,III,IV	0.246	0.574	.020	27	view →
ACC	OS	Tertile	IV	0.327	0.633	.045	18	view →
ESCA	OS	Tertile	II,III,IV	0.105	0.867	.016	18	view →

Pink = unfavorable, green = favorable. all 11 lineages →

GPR53P-BLCA (DFS)

Kaplan–Meier survival curve for GPR53P RNA expression in BLCA: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with GPR53P in patient tissues and cancer cell lines. In patient samples, GPR53P shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,744	STAD (5459)	view →
RNA	3,215	UCEC (1515)	view →